TY - GEN
T1 - Difference of Alzheimer's disease sub-groups using two features from intensity size zone matrix
AU - Lee, Seung Hak
AU - Park, Hyunjin
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/9/13
Y1 - 2017/9/13
N2 - Alzheimer's disease (AD) is known as one of the important diseases with worldwide impact. Unfortunately, we have not found the cause and treatment methods for AD. Magnetic resonance imaging (MRI) is an important research for AD research. Many recent studies focused on finding imaging biomarker associated with AD and mild cognitive impairment (MCI). Texture analysis jointly considers gray-level intensity and position of the voxels within a given region of interest (ROI). It can lead to better characterization of ROI than conventional approaches. We adopted one of the texture analysis methods called intensity size zone matrix (ISZM) to compare AD, late MCI (LMCI), early MCI (EMCI) and normal control (NC) subjects in both hemispheres of the hippocampus. As a result, we were able to distinguish among the sub-groups using the intensity variability feature and size zone variability feature computed from ISZM.
AB - Alzheimer's disease (AD) is known as one of the important diseases with worldwide impact. Unfortunately, we have not found the cause and treatment methods for AD. Magnetic resonance imaging (MRI) is an important research for AD research. Many recent studies focused on finding imaging biomarker associated with AD and mild cognitive impairment (MCI). Texture analysis jointly considers gray-level intensity and position of the voxels within a given region of interest (ROI). It can lead to better characterization of ROI than conventional approaches. We adopted one of the texture analysis methods called intensity size zone matrix (ISZM) to compare AD, late MCI (LMCI), early MCI (EMCI) and normal control (NC) subjects in both hemispheres of the hippocampus. As a result, we were able to distinguish among the sub-groups using the intensity variability feature and size zone variability feature computed from ISZM.
UR - https://www.scopus.com/pages/publications/85032171295
U2 - 10.1109/EMBC.2017.8037493
DO - 10.1109/EMBC.2017.8037493
M3 - Conference contribution
C2 - 29060534
AN - SCOPUS:85032171295
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 3020
EP - 3023
BT - 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
Y2 - 11 July 2017 through 15 July 2017
ER -