TY - GEN
T1 - Development of new combined system for production of FDG and NAF radiopharmaceuticals
AU - Dehghan, F.
AU - Jaloo, S.
AU - Afarideh, H.
AU - Ghergherehchi, M.
AU - Chai, J. S.
AU - Akhlaghi, M.
N1 - Publisher Copyright:
Copyright © 2013 CC-BY-3.0 and by the respective authors.
PY - 2014/3
Y1 - 2014/3
N2 - In this work, we present a new combined system which produces FDG and NaF in separate runs. The needed 18F for synthesis these radiopharmaceuticals are obtained by bombardment of highly enriched water (H2O18) with proton. The aim is development of routine systems to use with baby cyclotrons. In this study, the various chemical steps and required reagents as well as different reagent delivery methods has been investigated. This evaluation has been done with purpose of optimizing the performance of a conceptually simple device integrated into a fully automated synthesis procedure for radiosynthesis of FDG and NaF. In this system, we have used AVR microcontroller to control the process and LabVIEW software for monitoring the operation of system. Furthermore, Geiger Muller counters have been used to determine the activity to insure the accuracy of the systems operation.
AB - In this work, we present a new combined system which produces FDG and NaF in separate runs. The needed 18F for synthesis these radiopharmaceuticals are obtained by bombardment of highly enriched water (H2O18) with proton. The aim is development of routine systems to use with baby cyclotrons. In this study, the various chemical steps and required reagents as well as different reagent delivery methods has been investigated. This evaluation has been done with purpose of optimizing the performance of a conceptually simple device integrated into a fully automated synthesis procedure for radiosynthesis of FDG and NaF. In this system, we have used AVR microcontroller to control the process and LabVIEW software for monitoring the operation of system. Furthermore, Geiger Muller counters have been used to determine the activity to insure the accuracy of the systems operation.
KW - AVR microcontroller
KW - FDG and NAF radiopharmaceutical
KW - Geiger Muller counter
KW - Highly enriched water
KW - LabVIEW
UR - https://www.scopus.com/pages/publications/85076019431
M3 - Conference contribution
AN - SCOPUS:85076019431
T3 - CYCLOTRONS 2013 - Proceedings of the 20th International Conference on Cyclotrons and their Applications
SP - 390
EP - 392
BT - CYCLOTRONS 2013 - Proceedings of the 20th International Conference on Cyclotrons and their Applications
PB - Joint Accelerator Conferences Website (JACoW)
T2 - 20th International Conference on Cyclotrons and their Applications, CYCLOTRONS 2013
Y2 - 16 September 2013 through 20 September 2013
ER -