Decarboxylative acylation of indolines with α-keto acids under palladium catalysis: A facile strategy for the synthesis of 7-substituted indoles

Minyoung Kim, Neeraj Kumar Mishra, Jihye Park, Sangil Han, Youngmi Shin, Satyasheel Sharma, Youngil Lee, Eui Kyung Lee, Jong Hwan Kwak, In Su Kim

Research output: Contribution to journalArticlepeer-review

116 Scopus citations

Abstract

Palladium-catalyzed decarboxylative acylation of highly substituted indolines with α-keto acids via C–H bond activation is described. This protocol provides efficient access to C7-carbonylated indoles known to have diverse biological profiles.

Original languageEnglish
Pages (from-to)14249-14252
Number of pages4
JournalChemical Communications
Volume50
Issue number91
DOIs
StatePublished - 21 Oct 2014

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