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Cutaneous adverse effects associated with Iressa® (Gefitinib) medication

  • Jae Hong Park
  • , Jeong Joon Oh
  • , Yun Lim Choi
  • , Won Serk Kim
  • , Joo Heung Lee
  • , Eil Soo Lee
  • Sungkyunkwan University

Research output: Contribution to journalArticlepeer-review

Abstract

We report cutaneous adverse effects developed in three patients and are probably related to Iressa® (Gefitinib, ZD1839) medication. Iressa® is a new anti-cancer agent which acts by inhibiting epidermal growth factor (EGF) receptor signal transduction. The three patients had all taken Iressa® for treatment of non-small cell lung cancer and came to our clinic with cutaneous adverse effects. All three patients had acneiform eruptions, and one of the patients also had periungal granulation lesions. Histopathologically, periadnexal inflammatory cellular infiltrations were seen in the acneiform lesions of the three patients and granulation-like tissue proliferations in periungal granulation lesions of the one patient.

Original languageEnglish
Pages (from-to)92-95
Number of pages4
JournalKorean Journal of Dermatology
Volume43
Issue number1
StatePublished - Jan 2005
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Acneiform eruption
  • Cutaneous adverse effects
  • Iressa® (Gefitinib)
  • Periungal granulation lesion

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