Comparison of prognostic implications between the 7th and 8th edition of AJCC TNM staging system for head and neck soft-tissue sarcoma in adult patients

Hee Jung Kim; Nayeon Choi; Chung Hwan Baek; Young Ik Son; Han Sin Jeong; Man Ki Chung

doi:10.1007/s00405-019-05584-5

Comparison of prognostic implications between the 7th and 8th edition of AJCC TNM staging system for head and neck soft-tissue sarcoma in adult patients

Hee Jung Kim, Nayeon Choi, Chung Hwan Baek, Young Ik Son, Han Sin Jeong, Man Ki Chung

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Purpose: This study aimed to investigate the prognostic factors for head and neck soft-tissue sarcoma (HNSTS) in adults, with the comparisons between the 7th and 8th edition of AJCC TNM staging system. Methods: From a cancer registry of a single, tertiary referral medical center, the medical records of 67 patients treated from February 2005 to December 2017 were reviewed. Results: T1b stage by AJCC 7th edition showed most diverse stage migration by AJCC 8th edition, and T1a or T2b stage by 7th edition remained in T1–3 or T3–4 by 8th edition. T2 stage by 7th edition showed a significantly higher death rate than the T1 stage, with fair discrimination in overall survival. Higher histologic grade and angiosarcoma were significant prognostic factors for recurrence as well as overall survival. Also, nodal and distant metastasis worsen overall survival. Conclusions: In our series of patients with HNSTS, higher histologic grade, angiosarcoma, N1, and M1 stage significantly increased the risk of recurrence and worse overall survival, which was not evident in revised T stage by AJCC 8th edition.

Original language	English
Pages (from-to)	3195-3202
Number of pages	8
Journal	European Archives of Oto-Rhino-Laryngology
Volume	276
Issue number	11
DOIs	https://doi.org/10.1007/s00405-019-05584-5
State	Published - 1 Nov 2019
Externally published	Yes

Keywords

Head and neck
Prognostic factor
Sarcoma
Staging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00405-019-05584-5

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@article{0ccc8b3bd24743468b8fc784e3c4a05c,

title = "Comparison of prognostic implications between the 7th and 8th edition of AJCC TNM staging system for head and neck soft-tissue sarcoma in adult patients",

abstract = "Purpose: This study aimed to investigate the prognostic factors for head and neck soft-tissue sarcoma (HNSTS) in adults, with the comparisons between the 7th and 8th edition of AJCC TNM staging system. Methods: From a cancer registry of a single, tertiary referral medical center, the medical records of 67 patients treated from February 2005 to December 2017 were reviewed. Results: T1b stage by AJCC 7th edition showed most diverse stage migration by AJCC 8th edition, and T1a or T2b stage by 7th edition remained in T1–3 or T3–4 by 8th edition. T2 stage by 7th edition showed a significantly higher death rate than the T1 stage, with fair discrimination in overall survival. Higher histologic grade and angiosarcoma were significant prognostic factors for recurrence as well as overall survival. Also, nodal and distant metastasis worsen overall survival. Conclusions: In our series of patients with HNSTS, higher histologic grade, angiosarcoma, N1, and M1 stage significantly increased the risk of recurrence and worse overall survival, which was not evident in revised T stage by AJCC 8th edition.",

keywords = "Head and neck, Prognostic factor, Sarcoma, Staging",

author = "Kim, \{Hee Jung\} and Nayeon Choi and Baek, \{Chung Hwan\} and Son, \{Young Ik\} and Jeong, \{Han Sin\} and Chung, \{Man Ki\}",

note = "Publisher Copyright: {\textcopyright} 2019, Springer-Verlag GmbH Germany, part of Springer Nature.",

year = "2019",

month = nov,

day = "1",

doi = "10.1007/s00405-019-05584-5",

language = "English",

volume = "276",

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journal = "European Archives of Oto-Rhino-Laryngology",

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T1 - Comparison of prognostic implications between the 7th and 8th edition of AJCC TNM staging system for head and neck soft-tissue sarcoma in adult patients

AU - Kim, Hee Jung

AU - Choi, Nayeon

AU - Baek, Chung Hwan

AU - Son, Young Ik

AU - Jeong, Han Sin

AU - Chung, Man Ki

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Purpose: This study aimed to investigate the prognostic factors for head and neck soft-tissue sarcoma (HNSTS) in adults, with the comparisons between the 7th and 8th edition of AJCC TNM staging system. Methods: From a cancer registry of a single, tertiary referral medical center, the medical records of 67 patients treated from February 2005 to December 2017 were reviewed. Results: T1b stage by AJCC 7th edition showed most diverse stage migration by AJCC 8th edition, and T1a or T2b stage by 7th edition remained in T1–3 or T3–4 by 8th edition. T2 stage by 7th edition showed a significantly higher death rate than the T1 stage, with fair discrimination in overall survival. Higher histologic grade and angiosarcoma were significant prognostic factors for recurrence as well as overall survival. Also, nodal and distant metastasis worsen overall survival. Conclusions: In our series of patients with HNSTS, higher histologic grade, angiosarcoma, N1, and M1 stage significantly increased the risk of recurrence and worse overall survival, which was not evident in revised T stage by AJCC 8th edition.

AB - Purpose: This study aimed to investigate the prognostic factors for head and neck soft-tissue sarcoma (HNSTS) in adults, with the comparisons between the 7th and 8th edition of AJCC TNM staging system. Methods: From a cancer registry of a single, tertiary referral medical center, the medical records of 67 patients treated from February 2005 to December 2017 were reviewed. Results: T1b stage by AJCC 7th edition showed most diverse stage migration by AJCC 8th edition, and T1a or T2b stage by 7th edition remained in T1–3 or T3–4 by 8th edition. T2 stage by 7th edition showed a significantly higher death rate than the T1 stage, with fair discrimination in overall survival. Higher histologic grade and angiosarcoma were significant prognostic factors for recurrence as well as overall survival. Also, nodal and distant metastasis worsen overall survival. Conclusions: In our series of patients with HNSTS, higher histologic grade, angiosarcoma, N1, and M1 stage significantly increased the risk of recurrence and worse overall survival, which was not evident in revised T stage by AJCC 8th edition.

KW - Head and neck

KW - Prognostic factor

KW - Sarcoma

KW - Staging

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DO - 10.1007/s00405-019-05584-5

M3 - Article

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AN - SCOPUS:85070360292

SN - 0937-4477

VL - 276

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EP - 3202

JO - European Archives of Oto-Rhino-Laryngology

JF - European Archives of Oto-Rhino-Laryngology

IS - 11

ER -

Comparison of prognostic implications between the 7th and 8th edition of AJCC TNM staging system for head and neck soft-tissue sarcoma in adult patients

Abstract

Keywords

UN SDGs

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