Cerebral perfusion impairment in a patient with toluene abuse

Young Hoon Ryu; Jong Doo Lee; Pyeong Ho Yoon; Pyoung Jeon; Dong Ik Kim; Dong Won Shin

Cerebral perfusion impairment in a patient with toluene abuse

Young Hoon Ryu, Jong Doo Lee, Pyeong Ho Yoon, Pyoung Jeon, Dong Ik Kim, Dong Won Shin

Yonsei University

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

We report the case of a 17-yr-old man diagnosed as a toluene abuser. He had an 8-mo history of toluene inhalation exposure and was admitted to this hospital with symptoms of auditory and visual hallucination. Magnetic resonance imaging (MRI) revealed no structural abnormalities both on T1- and T2-weighted images, whereas SPECT using ^99mTc-ethyl cysteinate dimer (ECD) showed multifocally decreased perfusion in the cerebral cortex, basal ganglia and thalami. Our case indicates that SPECT detects early central nervous system injury from toluene inhalation even when neurological examination and neuroanatomic imaging such as MRI are normal.

Original language	English
Pages (from-to)	632-633
Number of pages	2
Journal	Journal of Nuclear Medicine
Volume	39
Issue number	4
State	Published - Apr 1998
Externally published	Yes

Keywords

Cerebral perfusion
Magnetic resonance imaging
SPECT
Technetium- 99m-ethyl cysteinate dimer
Toluene

Cite this

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title = "Cerebral perfusion impairment in a patient with toluene abuse",

abstract = "We report the case of a 17-yr-old man diagnosed as a toluene abuser. He had an 8-mo history of toluene inhalation exposure and was admitted to this hospital with symptoms of auditory and visual hallucination. Magnetic resonance imaging (MRI) revealed no structural abnormalities both on T1- and T2-weighted images, whereas SPECT using 99mTc-ethyl cysteinate dimer (ECD) showed multifocally decreased perfusion in the cerebral cortex, basal ganglia and thalami. Our case indicates that SPECT detects early central nervous system injury from toluene inhalation even when neurological examination and neuroanatomic imaging such as MRI are normal.",

keywords = "Cerebral perfusion, Magnetic resonance imaging, SPECT, Technetium- 99m-ethyl cysteinate dimer, Toluene",

author = "Ryu, \{Young Hoon\} and Lee, \{Jong Doo\} and Yoon, \{Pyeong Ho\} and Pyoung Jeon and Kim, \{Dong Ik\} and Shin, \{Dong Won\}",

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AU - Ryu, Young Hoon

AU - Lee, Jong Doo

AU - Yoon, Pyeong Ho

AU - Jeon, Pyoung

AU - Kim, Dong Ik

AU - Shin, Dong Won

PY - 1998/4

Y1 - 1998/4

N2 - We report the case of a 17-yr-old man diagnosed as a toluene abuser. He had an 8-mo history of toluene inhalation exposure and was admitted to this hospital with symptoms of auditory and visual hallucination. Magnetic resonance imaging (MRI) revealed no structural abnormalities both on T1- and T2-weighted images, whereas SPECT using 99mTc-ethyl cysteinate dimer (ECD) showed multifocally decreased perfusion in the cerebral cortex, basal ganglia and thalami. Our case indicates that SPECT detects early central nervous system injury from toluene inhalation even when neurological examination and neuroanatomic imaging such as MRI are normal.

AB - We report the case of a 17-yr-old man diagnosed as a toluene abuser. He had an 8-mo history of toluene inhalation exposure and was admitted to this hospital with symptoms of auditory and visual hallucination. Magnetic resonance imaging (MRI) revealed no structural abnormalities both on T1- and T2-weighted images, whereas SPECT using 99mTc-ethyl cysteinate dimer (ECD) showed multifocally decreased perfusion in the cerebral cortex, basal ganglia and thalami. Our case indicates that SPECT detects early central nervous system injury from toluene inhalation even when neurological examination and neuroanatomic imaging such as MRI are normal.

KW - Cerebral perfusion

KW - Magnetic resonance imaging

KW - SPECT

KW - Technetium- 99m-ethyl cysteinate dimer

KW - Toluene

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SN - 0161-5505

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JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

IS - 4

ER -

Cerebral perfusion impairment in a patient with toluene abuse

Abstract

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