Carotid intima-media thickness in Parkinson's disease

Jong Moon Lee; Kun Woo Park; Woo Keun Seo; Ho Park Moon; Changsu Han; Inho Jo; Ahn Jo Sangmee

doi:10.1002/mds.21757

Carotid intima-media thickness in Parkinson's disease

Jong Moon Lee
, Kun Woo Park
, Woo Keun Seo
, Ho Park Moon
, Changsu Han
, Inho Jo
, Ahn Jo Sangmee

Korea University
Ewha Womans University
Korea National Institute of Health

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ± 0.179 mm vs. 0.913 ± 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis.

Original language	English
Pages (from-to)	2446-2449
Number of pages	4
Journal	Movement Disorders
Volume	22
Issue number	16
DOIs	https://doi.org/10.1002/mds.21757
State	Published - Dec 2007
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Atherosclerosis
Intima-media thickness
Parkinson's disease

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10.1002/mds.21757

Cite this

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title = "Carotid intima-media thickness in Parkinson's disease",

abstract = "There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ± 0.179 mm vs. 0.913 ± 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis.",

keywords = "Atherosclerosis, Intima-media thickness, Parkinson's disease",

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year = "2007",

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doi = "10.1002/mds.21757",

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T1 - Carotid intima-media thickness in Parkinson's disease

AU - Lee, Jong Moon

AU - Park, Kun Woo

AU - Seo, Woo Keun

AU - Moon, Ho Park

AU - Han, Changsu

AU - Jo, Inho

AU - Sangmee, Ahn Jo

PY - 2007/12

Y1 - 2007/12

N2 - There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ± 0.179 mm vs. 0.913 ± 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis.

AB - There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ± 0.179 mm vs. 0.913 ± 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis.

KW - Atherosclerosis

KW - Intima-media thickness

KW - Parkinson's disease

UR - https://www.scopus.com/pages/publications/38549088384

U2 - 10.1002/mds.21757

DO - 10.1002/mds.21757

M3 - Article

C2 - 17960813

AN - SCOPUS:38549088384

SN - 0885-3185

VL - 22

SP - 2446

EP - 2449

JO - Movement Disorders

JF - Movement Disorders

IS - 16

ER -

Carotid intima-media thickness in Parkinson's disease

Abstract

UN SDGs

Keywords

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