Can the tumor neural niche be targeted to re-program cancer?

Erica K. Sloan; Joo Sang Lee

doi:10.1371/journal.pbio.3003266

Can the tumor neural niche be targeted to re-program cancer?

Erica K. Sloan
, Joo Sang Lee

Department of Precision Medicine

Monash University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Interactions between the peripheral nervous system and solid tumors influence cancer progression and treatment response. Defining the 3D tumor neural niche using spatial omics and AI technologies will identify new opportunities for targeted therapies to stop cancer progression.

Original language	English
Article number	e3003266
Journal	PLoS Biology
Volume	23
Issue number	7
DOIs	https://doi.org/10.1371/journal.pbio.3003266
State	Published - Jul 2025

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10.1371/journal.pbio.3003266

Cite this

@article{ff39b4c3c1164bff9ebd7b48c03c88ab,

title = "Can the tumor neural niche be targeted to re-program cancer?",

abstract = "Interactions between the peripheral nervous system and solid tumors influence cancer progression and treatment response. Defining the 3D tumor neural niche using spatial omics and AI technologies will identify new opportunities for targeted therapies to stop cancer progression.",

author = "Sloan, \{Erica K.\} and Lee, \{Joo Sang\}",

note = "Publisher Copyright: {\textcopyright} 2025 Sloan, Lee. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",

year = "2025",

month = jul,

doi = "10.1371/journal.pbio.3003266",

language = "English",

volume = "23",

journal = "PLoS Biology",

issn = "1544-9173",