Bioengineered skin-substitutes incorporating rete-ridges using a bioprinting process

  • Soo Jung Chae
  • , Seo Yul Jo
  • , Dogeon Yoon
  • , Ji Seon Lee
  • , Won Jin Kim
  • , Jae Yoon Lee
  • , Ji Hye Park
  • , You Rin Kim
  • , Wook Chun
  • , Geun Hyung Kim

Research output: Contribution to journalArticlepeer-review

Abstract

Highlights Collagen-fibrinogen based bioinks was prepared to fabricate 3D skin substitute. A mogul-shaped layer was developed to mimic the rete-ridges structure of skin. The enhanced in vitro cellular activities and mechanical properties were observed. The enhanced wound repair of skin substitutes in in vivo was observed.

Original languageEnglish
Article number015501
JournalInternational Journal of Extreme Manufacturing
Volume7
Issue number1
DOIs
StatePublished - 1 Feb 2025

Keywords

  • basement membrane
  • bioprinting
  • collagen
  • fibrinogen
  • skin substitute

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