Atypical presentations of MERS-CoV infection in immunocompromised hosts

Si Ho Kim; Jae Hoon Ko; Ga Eun Park; Sun Young Cho; Young Eun Ha; Ji Man Kang; Yae Jean Kim; Hee Jae Huh; Chang Seok Ki; Byeong Ho Jeong; Jinkyeong Park; Jun Ho Jang; Won Seog Kim; Cheol In Kang; Doo Ryeon Chung; Jae Hoon Song; Kyong Ran Peck

doi:10.1016/j.jiac.2017.04.004

Atypical presentations of MERS-CoV infection in immunocompromised hosts

Si Ho Kim, Jae Hoon Ko, Ga Eun Park, Sun Young Cho, Young Eun Ha, Ji Man Kang, Yae Jean Kim, Hee Jae Huh, Chang Seok Ki, Byeong Ho Jeong, Jinkyeong Park, Jun Ho Jang, Won Seog Kim, Cheol In Kang, Doo Ryeon Chung, Jae Hoon Song, Kyong Ran Peck

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

During the 2015 Korean MERS outbreak, we experienced atypical presentations of MERS-CoV infections in three immunocompromised hosts that warranted exceptional management. Case 1 showed delayed symptom development after a four-day asymptomatic period, Case 2 experienced a 20-day incubation period, and Case 3 exhibited persistent viral shedding without clinical deterioration. Recognizing these exceptions is extremely important in the management of MERS-CoV-exposed or -infected patients and for control of potential MERS outbreaks.

Original language	English
Pages (from-to)	769-773
Number of pages	5
Journal	Journal of Infection and Chemotherapy
Volume	23
Issue number	11
DOIs	https://doi.org/10.1016/j.jiac.2017.04.004
State	Published - Nov 2017
Externally published	Yes

Keywords

Asymptomatic period
Corticosteroid
Immunocompromised host
Incubation period
Middle East respiratory syndrome coronavirus

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jiac.2017.04.004

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Kim, S. H., Ko, J. H., Park, G. E., Cho, S. Y., Ha, Y. E., Kang, J. M., Kim, Y. J., Huh, H. J., Ki, C. S., Jeong, B. H., Park, J., Jang, J. H., Kim, W. S., Kang, C. I., Chung, D. R., Song, J. H., & Peck, K. R. (2017). Atypical presentations of MERS-CoV infection in immunocompromised hosts. Journal of Infection and Chemotherapy, 23(11), 769-773. https://doi.org/10.1016/j.jiac.2017.04.004

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title = "Atypical presentations of MERS-CoV infection in immunocompromised hosts",

abstract = "During the 2015 Korean MERS outbreak, we experienced atypical presentations of MERS-CoV infections in three immunocompromised hosts that warranted exceptional management. Case 1 showed delayed symptom development after a four-day asymptomatic period, Case 2 experienced a 20-day incubation period, and Case 3 exhibited persistent viral shedding without clinical deterioration. Recognizing these exceptions is extremely important in the management of MERS-CoV-exposed or -infected patients and for control of potential MERS outbreaks.",

keywords = "Asymptomatic period, Corticosteroid, Immunocompromised host, Incubation period, Middle East respiratory syndrome coronavirus",

author = "Kim, \{Si Ho\} and Ko, \{Jae Hoon\} and Park, \{Ga Eun\} and Cho, \{Sun Young\} and Ha, \{Young Eun\} and Kang, \{Ji Man\} and Kim, \{Yae Jean\} and Huh, \{Hee Jae\} and Ki, \{Chang Seok\} and Jeong, \{Byeong Ho\} and Jinkyeong Park and Jang, \{Jun Ho\} and Kim, \{Won Seog\} and Kang, \{Cheol In\} and Chung, \{Doo Ryeon\} and Song, \{Jae Hoon\} and Peck, \{Kyong Ran\}",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2017",

month = nov,

doi = "10.1016/j.jiac.2017.04.004",

language = "English",

volume = "23",

pages = "769--773",

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TY - JOUR

T1 - Atypical presentations of MERS-CoV infection in immunocompromised hosts

AU - Kim, Si Ho

AU - Ko, Jae Hoon

AU - Park, Ga Eun

AU - Cho, Sun Young

AU - Ha, Young Eun

AU - Kang, Ji Man

AU - Kim, Yae Jean

AU - Huh, Hee Jae

AU - Ki, Chang Seok

AU - Jeong, Byeong Ho

AU - Park, Jinkyeong

AU - Jang, Jun Ho

AU - Kim, Won Seog

AU - Kang, Cheol In

AU - Chung, Doo Ryeon

AU - Song, Jae Hoon

AU - Peck, Kyong Ran

PY - 2017/11

Y1 - 2017/11

N2 - During the 2015 Korean MERS outbreak, we experienced atypical presentations of MERS-CoV infections in three immunocompromised hosts that warranted exceptional management. Case 1 showed delayed symptom development after a four-day asymptomatic period, Case 2 experienced a 20-day incubation period, and Case 3 exhibited persistent viral shedding without clinical deterioration. Recognizing these exceptions is extremely important in the management of MERS-CoV-exposed or -infected patients and for control of potential MERS outbreaks.

AB - During the 2015 Korean MERS outbreak, we experienced atypical presentations of MERS-CoV infections in three immunocompromised hosts that warranted exceptional management. Case 1 showed delayed symptom development after a four-day asymptomatic period, Case 2 experienced a 20-day incubation period, and Case 3 exhibited persistent viral shedding without clinical deterioration. Recognizing these exceptions is extremely important in the management of MERS-CoV-exposed or -infected patients and for control of potential MERS outbreaks.

KW - Asymptomatic period

KW - Corticosteroid

KW - Immunocompromised host

KW - Incubation period

KW - Middle East respiratory syndrome coronavirus

UR - https://www.scopus.com/pages/publications/85019539061

U2 - 10.1016/j.jiac.2017.04.004

DO - 10.1016/j.jiac.2017.04.004

M3 - Article

C2 - 28545936

AN - SCOPUS:85019539061

SN - 1341-321X

VL - 23

SP - 769

EP - 773

JO - Journal of Infection and Chemotherapy

JF - Journal of Infection and Chemotherapy

IS - 11

ER -

Atypical presentations of MERS-CoV infection in immunocompromised hosts

Abstract

Keywords

UN SDGs

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