Asarotonide, a new phenylpropanoid with a rare natural acetonide group from the rhizomes of Acorus gramineus

Jae Sik Yu; Eunjung Moon; Sang Un Choi; Ki Hyun Kim

doi:10.1016/j.tetlet.2016.03.010

Asarotonide, a new phenylpropanoid with a rare natural acetonide group from the rhizomes of Acorus gramineus

Jae Sik Yu
, Eunjung Moon
, Sang Un Choi
, Ki Hyun Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

A new phenylpropanoid with a rare natural acetonide group, asarotonide, together with three known phenylpropanoids were isolated from the rhizomes of Acorus gramineus. The structure of the new compound was established by extensive spectroscopic data and HR-MS. The antiproliferative activities of the compounds were tested against human cancer cell lines; in addition, inhibitory activities on nitric oxide production were evaluated in an activated murine microglial cell line.

Original language	English
Pages (from-to)	1699-1701
Number of pages	3
Journal	Tetrahedron Letters
Volume	57
Issue number	15
DOIs	https://doi.org/10.1016/j.tetlet.2016.03.010
State	Published - 13 Apr 2016

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

InChIKey PTBGHAVCLHAXNU-LKFCYVNXSA-N

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10.1016/j.tetlet.2016.03.010

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title = "Asarotonide, a new phenylpropanoid with a rare natural acetonide group from the rhizomes of Acorus gramineus",

abstract = "A new phenylpropanoid with a rare natural acetonide group, asarotonide, together with three known phenylpropanoids were isolated from the rhizomes of Acorus gramineus. The structure of the new compound was established by extensive spectroscopic data and HR-MS. The antiproliferative activities of the compounds were tested against human cancer cell lines; in addition, inhibitory activities on nitric oxide production were evaluated in an activated murine microglial cell line.",

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author = "Yu, \{Jae Sik\} and Eunjung Moon and Choi, \{Sang Un\} and Kim, \{Ki Hyun\}",

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year = "2016",

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doi = "10.1016/j.tetlet.2016.03.010",

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T1 - Asarotonide, a new phenylpropanoid with a rare natural acetonide group from the rhizomes of Acorus gramineus

AU - Yu, Jae Sik

AU - Moon, Eunjung

AU - Choi, Sang Un

AU - Kim, Ki Hyun

PY - 2016/4/13

Y1 - 2016/4/13

N2 - A new phenylpropanoid with a rare natural acetonide group, asarotonide, together with three known phenylpropanoids were isolated from the rhizomes of Acorus gramineus. The structure of the new compound was established by extensive spectroscopic data and HR-MS. The antiproliferative activities of the compounds were tested against human cancer cell lines; in addition, inhibitory activities on nitric oxide production were evaluated in an activated murine microglial cell line.

AB - A new phenylpropanoid with a rare natural acetonide group, asarotonide, together with three known phenylpropanoids were isolated from the rhizomes of Acorus gramineus. The structure of the new compound was established by extensive spectroscopic data and HR-MS. The antiproliferative activities of the compounds were tested against human cancer cell lines; in addition, inhibitory activities on nitric oxide production were evaluated in an activated murine microglial cell line.

KW - InChIKey PTBGHAVCLHAXNU-LKFCYVNXSA-N

UR - https://www.scopus.com/pages/publications/84960155489

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DO - 10.1016/j.tetlet.2016.03.010

M3 - Article

AN - SCOPUS:84960155489

SN - 0040-4039

VL - 57

SP - 1699

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 15

ER -

Asarotonide, a new phenylpropanoid with a rare natural acetonide group from the rhizomes of Acorus gramineus

Abstract

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Keywords

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