Anatomical and Functional Outcomes of Prolift Transvaginal Mesh for Treatment of Pelvic Organ Prolapse

Objectives: To evaluate anatomical and functional outcomes of the Prolift Transvaginal Mesh for treatment of pelvic organ prolapse (POP) with regard to safety and satisfaction. Methods: We reviewed the medical records of 163 patients who underwent POP repair with Prolift Transvaginal Mesh between December 2005 and March 2012. An “optimal” anatomic outcome was defined as Pelvic Organ Prolapse Quantification System (POP-Q) stage 0, and a “satisfactory” anatomic outcome was defined as POP-Q stage 1. Resuts: A total of 163 patients were included in this study, with a mean age (range) of 61.6 (35–83) years. An anterior mesh was used in 110 patients, and combined anterior and posterior mesh was used in 53 patients. The mean follow-up period after POP repair was 40.4 (12–63) months. Optimal anatomic outcomes for anterior, apical, and posterior prolapse were achieved in 55.9, 69.2, and 65.8% of cases, respectively. Optimal or satisfactory anatomic outcomes for anterior, apical, and posterior prolapse occurred in 76.7, 85.0, and 82.5% of cases, respectively. Mean values for points in the POP-Q, urinary distress inventory (UDI), and pelvic organ prolapsed distress inventory (POPDI) in the Pelvic Floor Distress Inventory (PFDI) were all significantly improved after the operation. The overall satisfaction rate for the operation was 84.7%. Five patients (3.1%) were diagnosed with vaginal erosion and treated with partial excision of the mesh without evidence of infection. Conclusions: Pelvic organ prolapse repair using Prolift Transvaginal Mesh is an effective and safe procedure without significant complications.