An Injectable 64 nW ECG Mixed-Signal SoC in 65 nm for Arrhythmia Monitoring

Yen Po Chen; Dongsuk Jeon; Yoonmyung Lee; Yejoong Kim; Zhiyoong Foo; Inhee Lee; Nicholas B. Langhals; Grant Kruger; Hakan Oral; Omer Berenfeld; Zhengya Zhang; David Blaauw; Dennis Sylvester

doi:10.1109/JSSC.2014.2364036

An Injectable 64 nW ECG Mixed-Signal SoC in 65 nm for Arrhythmia Monitoring

Yen Po Chen
, Dongsuk Jeon
, Yoonmyung Lee
, Yejoong Kim
, Zhiyoong Foo
, Inhee Lee
, Nicholas B. Langhals
, Grant Kruger
, Hakan Oral
, Omer Berenfeld
, Zhengya Zhang
, David Blaauw
, Dennis Sylvester

Department of Semiconductor Systems Engineering

University of Michigan, Ann Arbor

Research output: Contribution to journal › Article › peer-review

165 Scopus citations

Abstract

A syringe-implantable electrocardiography (ECG) monitoring system is proposed. The noise optimization and circuit techniques in the analog front-end (AFE) enable 31 nA current consumption while a minimum energy computation approach in the digital back-end reduces digital energy consumption by 40%. The proposed SoC is fabricated in 65 nm CMOS and consumes 64 nW while successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.

Original language	English
Article number	6957602
Pages (from-to)	375-390
Number of pages	16
Journal	IEEE Journal of Solid-State Circuits
Volume	50
Issue number	1
DOIs	https://doi.org/10.1109/JSSC.2014.2364036
State	Published - 1 Jan 2015

Keywords

Analog front-end (AFE)
asynchronous logic
capacitive feedback chopper stabilized instrumental amplifier (CCIA)
electrocardiography (ECG)
fast Fourier transform (FFT)
implantable system
kickback noise
minimum energy point (MEP)
mm

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10.1109/JSSC.2014.2364036

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title = "An Injectable 64 nW ECG Mixed-Signal SoC in 65 nm for Arrhythmia Monitoring",

abstract = "A syringe-implantable electrocardiography (ECG) monitoring system is proposed. The noise optimization and circuit techniques in the analog front-end (AFE) enable 31 nA current consumption while a minimum energy computation approach in the digital back-end reduces digital energy consumption by 40\%. The proposed SoC is fabricated in 65 nm CMOS and consumes 64 nW while successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.",

keywords = "Analog front-end (AFE), asynchronous logic, capacitive feedback chopper stabilized instrumental amplifier (CCIA), electrocardiography (ECG), fast Fourier transform (FFT), implantable system, kickback noise, minimum energy point (MEP), mm",

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AU - Kim, Yejoong

AU - Foo, Zhiyoong

AU - Lee, Inhee

AU - Langhals, Nicholas B.

AU - Kruger, Grant

AU - Oral, Hakan

AU - Berenfeld, Omer

AU - Zhang, Zhengya

AU - Blaauw, David

AU - Sylvester, Dennis

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AB - A syringe-implantable electrocardiography (ECG) monitoring system is proposed. The noise optimization and circuit techniques in the analog front-end (AFE) enable 31 nA current consumption while a minimum energy computation approach in the digital back-end reduces digital energy consumption by 40%. The proposed SoC is fabricated in 65 nm CMOS and consumes 64 nW while successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.

KW - Analog front-end (AFE)

KW - asynchronous logic

KW - capacitive feedback chopper stabilized instrumental amplifier (CCIA)

KW - electrocardiography (ECG)

KW - fast Fourier transform (FFT)

KW - implantable system

KW - kickback noise

KW - minimum energy point (MEP)

KW - mm

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An Injectable 64 nW ECG Mixed-Signal SoC in 65 nm for Arrhythmia Monitoring

Abstract

Keywords

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