An efficient stereoselective synthesis of (+)-deoxoprosophylline

In Su Kim; Chae Baek Ryu; Qing Ri Li; Ok Pyo Zee; Young Hoon Jung

doi:10.1016/j.tetlet.2007.07.034

An efficient stereoselective synthesis of (+)-deoxoprosophylline

In Su Kim, Chae Baek Ryu, Qing Ri Li, Ok Pyo Zee, Young Hoon Jung

Department of Pharmacy

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

An efficient stereoselective synthesis of (+)-deoxoprosophylline from readily available p-anisaldehyde is described. Key steps in the synthesis include the stereoselective amination of anti-1,2-dibenzyl ether using chlorosulfonyl isocyanate, intermolecular olefination, and Pd-catalyzed intramolecular cyclization.

Original language	English
Pages (from-to)	6258-6261
Number of pages	4
Journal	Tetrahedron Letters
Volume	48
Issue number	36
DOIs	https://doi.org/10.1016/j.tetlet.2007.07.034
State	Published - 3 Sep 2007

Keywords

Chlorosulfonyl isocyanate
Deoxoprosophylline
Intermolecular olefination
Intramolecular cyclization

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10.1016/j.tetlet.2007.07.034

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title = "An efficient stereoselective synthesis of (+)-deoxoprosophylline",

abstract = "An efficient stereoselective synthesis of (+)-deoxoprosophylline from readily available p-anisaldehyde is described. Key steps in the synthesis include the stereoselective amination of anti-1,2-dibenzyl ether using chlorosulfonyl isocyanate, intermolecular olefination, and Pd-catalyzed intramolecular cyclization.",

keywords = "Chlorosulfonyl isocyanate, Deoxoprosophylline, Intermolecular olefination, Intramolecular cyclization",

author = "Kim, \{In Su\} and Ryu, \{Chae Baek\} and Li, \{Qing Ri\} and Zee, \{Ok Pyo\} and Jung, \{Young Hoon\}",

year = "2007",

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doi = "10.1016/j.tetlet.2007.07.034",

language = "English",

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T1 - An efficient stereoselective synthesis of (+)-deoxoprosophylline

AU - Kim, In Su

AU - Ryu, Chae Baek

AU - Li, Qing Ri

AU - Zee, Ok Pyo

AU - Jung, Young Hoon

PY - 2007/9/3

Y1 - 2007/9/3

N2 - An efficient stereoselective synthesis of (+)-deoxoprosophylline from readily available p-anisaldehyde is described. Key steps in the synthesis include the stereoselective amination of anti-1,2-dibenzyl ether using chlorosulfonyl isocyanate, intermolecular olefination, and Pd-catalyzed intramolecular cyclization.

AB - An efficient stereoselective synthesis of (+)-deoxoprosophylline from readily available p-anisaldehyde is described. Key steps in the synthesis include the stereoselective amination of anti-1,2-dibenzyl ether using chlorosulfonyl isocyanate, intermolecular olefination, and Pd-catalyzed intramolecular cyclization.

KW - Chlorosulfonyl isocyanate

KW - Deoxoprosophylline

KW - Intermolecular olefination

KW - Intramolecular cyclization

UR - https://www.scopus.com/pages/publications/34547682313

U2 - 10.1016/j.tetlet.2007.07.034

DO - 10.1016/j.tetlet.2007.07.034

M3 - Article

AN - SCOPUS:34547682313

SN - 0040-4039

VL - 48

SP - 6258

EP - 6261

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 36

ER -

An efficient stereoselective synthesis of (+)-deoxoprosophylline

Abstract

Keywords

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