TY - JOUR
T1 - A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation
AU - International Islet Transplant Centers
AU - European Islet and Pancreas Transplant Association (EPITA)
AU - International Islet and Pancreas Transplant Association (IPITA)
AU - Berney, Thierry
AU - Andres, Axel
AU - Bellin, Melena D.
AU - de Koning, Eelco J.P.
AU - Johnson, Paul R.V.
AU - Kay, Thomas W.H.
AU - Lundgren, Torbjörn
AU - Rickels, Michael R.
AU - Scholz, Hanne
AU - Stock, Peter G.
AU - White, Steve
AU - Aghayan, Hamid R.
AU - Alejandro, Rodolfo
AU - Ricordi, Camillo
AU - Anazawa, Takayuki
AU - Armanet, Mathieu
AU - Cattan, Pierre
AU - Badet, Lionel
AU - Buron, Fanny
AU - Balamurugan, Appakalai N.
AU - Mokshagundam, Sri Prakash L.
AU - Barton, Franca B.
AU - Benhamou, Pierre Y.
AU - Lablanche, Sandrine
AU - Berishvili, Ekaterine
AU - Bosco, Domenico
AU - Pernin, Nadine
AU - Wassmer, Charles H.
AU - Bertuzzi, Federico
AU - Borot, Sophie
AU - Bottino, Rita
AU - Brendel, Mathias D.
AU - Caicedo, Luis Armando
AU - Echeverri, Gabriel J.
AU - Casey, John
AU - Choudhary, Pratik
AU - Coates, Patrick T.
AU - Conget, Ignacio
AU - Ventura-Aguiar, Pedro
AU - Cooper, Matthew
AU - Khan, Khalid M.
AU - Debska-Slizien, Alicja
AU - Golebiewska, Justyna
AU - Desai, Chirag S.
AU - Dominguez-Gil, Beatriz
AU - Drago, Julian
AU - Hyon, Sung H.
AU - Fedaruk, Dzmitry
AU - Goss, John A.
AU - Kim, Jae H.
N1 - Publisher Copyright:
Copyright © 2022 Berney, Andres, Bellin, de Koning, Johnson, Kay, Lundgren, Rickels, Scholz, Stock, White and the International Islet Transplant Centers.
PY - 2022/8/11
Y1 - 2022/8/11
N2 - A global online survey was administered to 69 islet transplantation programs, covering 84 centers and 5 networks. The survey addressed questions on program organization and activity in the 2000–2020 period, including impact on activity of national health care coverage policies. We obtained full data from 55 institutions or networks worldwide and basic activity data from 6 centers. Additional data were obtained from alternative sources. A total of 94 institutions and 5 networks was identified as having performed islet allotransplantation. 4,365 islet allotransplants (2,608 in Europe, 1,475 in North America, 135 in Asia, 119 in Oceania, 28 in South America) were reported in 2,170 patients in the survey period. From 15 centers active at the start of the study period, the number of simultaneously active islet centers peaked at 54, to progressively decrease to 26 having performed islet allotransplants in 2020. Notably, only 16 centers/networks have done >100 islet allotransplants in the survey period. Types of transplants performed differed notably between North America and the rest of the world, in particular with respect to the near-absence of simultaneous islet-kidney transplantation. Absence of heath care coverage has significantly hampered transplant activity in the past years and the COVID-19 pandemic in 2020.
AB - A global online survey was administered to 69 islet transplantation programs, covering 84 centers and 5 networks. The survey addressed questions on program organization and activity in the 2000–2020 period, including impact on activity of national health care coverage policies. We obtained full data from 55 institutions or networks worldwide and basic activity data from 6 centers. Additional data were obtained from alternative sources. A total of 94 institutions and 5 networks was identified as having performed islet allotransplantation. 4,365 islet allotransplants (2,608 in Europe, 1,475 in North America, 135 in Asia, 119 in Oceania, 28 in South America) were reported in 2,170 patients in the survey period. From 15 centers active at the start of the study period, the number of simultaneously active islet centers peaked at 54, to progressively decrease to 26 having performed islet allotransplants in 2020. Notably, only 16 centers/networks have done >100 islet allotransplants in the survey period. Types of transplants performed differed notably between North America and the rest of the world, in particular with respect to the near-absence of simultaneous islet-kidney transplantation. Absence of heath care coverage has significantly hampered transplant activity in the past years and the COVID-19 pandemic in 2020.
KW - activity
KW - health care coverage
KW - IAK
KW - indications
KW - islet transplantation
KW - ITA
KW - SIK
KW - type 1 diabetes mellitus
UR - https://www.scopus.com/pages/publications/85136599446
U2 - 10.3389/ti.2022.10507
DO - 10.3389/ti.2022.10507
M3 - Article
C2 - 36033644
AN - SCOPUS:85136599446
SN - 0934-0874
VL - 35
JO - Transplant International
JF - Transplant International
M1 - 10507
ER -
SDG 3 Good Health and Well-being