A versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via a combination of enzymatic and chemical processes

Young Ger Suh; Kyung Hoon Min; Yong Sil Lee; Seung Yong Seo; Seok Ho Kim; Hyun Ju Park

doi:10.1016/S0040-4039(02)00670-6

A versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via a combination of enzymatic and chemical processes

Young Ger Suh
, Kyung Hoon Min
, Yong Sil Lee
, Seung Yong Seo
, Seok Ho Kim
, Hyun Ju Park

Department of Pharmacy

Seoul National University

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

This paper describes a versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via enzymatic kinetic resolution of the key allylic alcohol synthon and the facile introduction of three alkyne units which were concomitantly converted to three alkenes units.

Original language	English
Pages (from-to)	3825-3828
Number of pages	4
Journal	Tetrahedron Letters
Volume	43
Issue number	21
DOIs	https://doi.org/10.1016/S0040-4039(02)00670-6
State	Published - 20 May 2002

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title = "A versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via a combination of enzymatic and chemical processes",

abstract = "This paper describes a versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via enzymatic kinetic resolution of the key allylic alcohol synthon and the facile introduction of three alkyne units which were concomitantly converted to three alkenes units.",

author = "Suh, \{Young Ger\} and Min, \{Kyung Hoon\} and Lee, \{Yong Sil\} and Seo, \{Seung Yong\} and Kim, \{Seok Ho\} and Park, \{Hyun Ju\}",

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T1 - A versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via a combination of enzymatic and chemical processes

AU - Suh, Young Ger

AU - Min, Kyung Hoon

AU - Lee, Yong Sil

AU - Seo, Seung Yong

AU - Kim, Seok Ho

AU - Park, Hyun Ju

PY - 2002/5/20

Y1 - 2002/5/20

N2 - This paper describes a versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via enzymatic kinetic resolution of the key allylic alcohol synthon and the facile introduction of three alkyne units which were concomitantly converted to three alkenes units.

AB - This paper describes a versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via enzymatic kinetic resolution of the key allylic alcohol synthon and the facile introduction of three alkyne units which were concomitantly converted to three alkenes units.

UR - https://www.scopus.com/pages/publications/0037140875

U2 - 10.1016/S0040-4039(02)00670-6

DO - 10.1016/S0040-4039(02)00670-6

M3 - Article

AN - SCOPUS:0037140875

SN - 0040-4039

VL - 43

SP - 3825

EP - 3828

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 21

ER -

A versatile asymmetric synthesis of highly enantiomerically enriched 12(S)-HETE via a combination of enzymatic and chemical processes

Abstract

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