A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

Myoung Ja Lee; Dong Youn Jeong; Woo Seong Kim; Hyun Dae Kim; Cheorl Ho Kim; Won Whan Park; Yong Ha Park; Kyung Sam Kim; Hyung Min Kim; Dong Soo Kim

doi:10.1128/AEM.66.4.1698-1701.2000

A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

Myoung Ja Lee, Dong Youn Jeong, Woo Seong Kim, Hyun Dae Kim, Cheorl Ho Kim, Won Whan Park, Yong Ha Park, Kyung Sam Kim, Hyung Min Kim, Dong Soo Kim

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

Abstract

Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

Original language	English
Pages (from-to)	1698-1701
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	66
Issue number	4
DOIs	https://doi.org/10.1128/AEM.66.4.1698-1701.2000
State	Published - Apr 2000
Externally published	Yes

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10.1128/AEM.66.4.1698-1701.2000

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title = "A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus",

abstract = "Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.",

author = "Lee, \{Myoung Ja\} and Jeong, \{Dong Youn\} and Kim, \{Woo Seong\} and Kim, \{Hyun Dae\} and Kim, \{Cheorl Ho\} and Park, \{Won Whan\} and Park, \{Yong Ha\} and Kim, \{Kyung Sam\} and Kim, \{Hyung Min\} and Kim, \{Dong Soo\}",

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language = "English",

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T1 - A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

AU - Lee, Myoung Ja

AU - Jeong, Dong Youn

AU - Kim, Woo Seong

AU - Kim, Hyun Dae

AU - Kim, Cheorl Ho

AU - Park, Won Whan

AU - Park, Yong Ha

AU - Kim, Kyung Sam

AU - Kim, Hyung Min

AU - Kim, Dong Soo

PY - 2000/4

Y1 - 2000/4

N2 - Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

AB - Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

UR - https://www.scopus.com/pages/publications/0034106341

U2 - 10.1128/AEM.66.4.1698-1701.2000

DO - 10.1128/AEM.66.4.1698-1701.2000

M3 - Article

C2 - 10742263

AN - SCOPUS:0034106341

SN - 0099-2240

VL - 66

SP - 1698

EP - 1701

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 4

ER -

A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

Abstract

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