A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

Myoung Ja Lee; Dong Youn Jeong; Woo Seong Kim; Hyun Dae Kim; Cheorl Ho Kim; Won Whan Park; Yong Ha Park; Kyung Sam Kim; Hyung Min Kim; Dong Soo Kim

doi:10.1128/AEM.66.4.1698-1701.2000

A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

Myoung Ja Lee
, Dong Youn Jeong
, Woo Seong Kim
, Hyun Dae Kim
, Cheorl Ho Kim
, Won Whan Park
, Yong Ha Park
, Kyung Sam Kim
, Hyung Min Kim
, Dong Soo Kim

Dongguk University
Kyungsung University
Pusan Regional FDA
Dong-Pusan Coll
Korea Research Institute of Bioscience and Biotechnology
Pusan Women's College
Wonkwang University

Research output: Contribution to journal › Article › peer-review

98 Scopus citations

Abstract

Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

Original language	English
Pages (from-to)	1698-1701
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	66
Issue number	4
DOIs	https://doi.org/10.1128/AEM.66.4.1698-1701.2000
State	Published - Apr 2000
Externally published	Yes

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10.1128/AEM.66.4.1698-1701.2000

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title = "A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus",

abstract = "Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.",

author = "Lee, \{Myoung Ja\} and Jeong, \{Dong Youn\} and Kim, \{Woo Seong\} and Kim, \{Hyun Dae\} and Kim, \{Cheorl Ho\} and Park, \{Won Whan\} and Park, \{Yong Ha\} and Kim, \{Kyung Sam\} and Kim, \{Hyung Min\} and Kim, \{Dong Soo\}",

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doi = "10.1128/AEM.66.4.1698-1701.2000",

language = "English",

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T1 - A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

AU - Lee, Myoung Ja

AU - Jeong, Dong Youn

AU - Kim, Woo Seong

AU - Kim, Hyun Dae

AU - Kim, Cheorl Ho

AU - Park, Won Whan

AU - Park, Yong Ha

AU - Kim, Kyung Sam

AU - Kim, Hyung Min

AU - Kim, Dong Soo

PY - 2000/4

Y1 - 2000/4

N2 - Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

AB - Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced Trx, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

UR - https://www.scopus.com/pages/publications/0034106341

U2 - 10.1128/AEM.66.4.1698-1701.2000

DO - 10.1128/AEM.66.4.1698-1701.2000

M3 - Article

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AN - SCOPUS:0034106341

SN - 0099-2240

VL - 66

SP - 1698

EP - 1701

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 4

ER -

A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus

Abstract

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