A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb2Se9 using poloxamer

Sudong Chae; Seungbae Oh; Kyung Hwan Choi; Jin Woong Lee; Jiho Jeon; Zhixiang Liu; Cong Wang; Changmo Lim; Xue Dong; Chaeheon Woo; Ghulam Asghar; Liyi Shi; Joohoon Kang; Sung Jae Kim; Si Young Song; Jung Heon Lee; Hak Ki Yu; Jae Young Choi

doi:10.1038/s41598-020-80730-2

A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb₂Se₉ using poloxamer

Sudong Chae
, Seungbae Oh
, Kyung Hwan Choi
, Jin Woong Lee
, Jiho Jeon
, Zhixiang Liu
, Cong Wang
, Changmo Lim
, Xue Dong
, Chaeheon Woo
, Ghulam Asghar
, Liyi Shi
, Joohoon Kang
, Sung Jae Kim
, Si Young Song
, Jung Heon Lee
, Hak Ki Yu
, Jae Young Choi

Department of Advanced Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

In this research, dispersion of a new type of one-dimensional inorganic material Nb₂Se₉, composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb₂Se₉, which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb₂Se₉, and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb₂Se₉ to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb₂Se₉ using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.

Original language	English
Article number	176
Journal	Scientific Reports
Volume	11
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-80730-2
State	Published - Dec 2021

Access to Document

10.1038/s41598-020-80730-2

Cite this

Chae, S., Oh, S., Choi, K. H., Lee, J. W., Jeon, J., Liu, Z., Wang, C., Lim, C., Dong, X., Woo, C., Asghar, G., Shi, L., Kang, J., Kim, S. J., Song, S. Y., Lee, J. H., Yu, H. K., & Choi, J. Y. (2021). A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb₂Se₉ using poloxamer. Scientific Reports, 11(1), Article 176. https://doi.org/10.1038/s41598-020-80730-2

@article{37c06ffeabd4436a95b81f8e0910bf75,

title = "A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb2Se9 using poloxamer",

abstract = "In this research, dispersion of a new type of one-dimensional inorganic material Nb2Se9, composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb2Se9, which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb2Se9, and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb2Se9 to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb2Se9 using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.",

author = "Sudong Chae and Seungbae Oh and Choi, \{Kyung Hwan\} and Lee, \{Jin Woong\} and Jiho Jeon and Zhixiang Liu and Cong Wang and Changmo Lim and Xue Dong and Chaeheon Woo and Ghulam Asghar and Liyi Shi and Joohoon Kang and Kim, \{Sung Jae\} and Song, \{Si Young\} and Lee, \{Jung Heon\} and Yu, \{Hak Ki\} and Choi, \{Jae Young\}",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

month = dec,

doi = "10.1038/s41598-020-80730-2",

language = "English",

volume = "11",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Research",

number = "1",

}

TY - JOUR

T1 - A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb2Se9 using poloxamer

AU - Chae, Sudong

AU - Oh, Seungbae

AU - Choi, Kyung Hwan

AU - Lee, Jin Woong

AU - Jeon, Jiho

AU - Liu, Zhixiang

AU - Wang, Cong

AU - Lim, Changmo

AU - Dong, Xue

AU - Woo, Chaeheon

AU - Asghar, Ghulam

AU - Shi, Liyi

AU - Kang, Joohoon

AU - Kim, Sung Jae

AU - Song, Si Young

AU - Lee, Jung Heon

AU - Yu, Hak Ki

AU - Choi, Jae Young

PY - 2021/12

Y1 - 2021/12

N2 - In this research, dispersion of a new type of one-dimensional inorganic material Nb2Se9, composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb2Se9, which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb2Se9, and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb2Se9 to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb2Se9 using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.

AB - In this research, dispersion of a new type of one-dimensional inorganic material Nb2Se9, composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb2Se9, which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb2Se9, and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb2Se9 to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb2Se9 using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.

UR - https://www.scopus.com/pages/publications/85098970780

U2 - 10.1038/s41598-020-80730-2

DO - 10.1038/s41598-020-80730-2

M3 - Article

C2 - 33420413

AN - SCOPUS:85098970780

SN - 2045-2322

VL - 11

JO - Scientific Reports

JF - Scientific Reports

IS - 1

M1 - 176

ER -

A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb₂Se₉ using poloxamer

Abstract

Access to Document

Other files and links

Fingerprint

Cite this