A Plasmid bearing the blaCTX-M-15 gene and phage P1-like sequences from a sequence type 11 Klebsiella pneumoniae isolate

Juyoun Shin; Kwan Soo Ko

doi:10.1128/AAC.00265-15

A Plasmid bearing the bla_CTX-M-15 gene and phage P1-like sequences from a sequence type 11 Klebsiella pneumoniae isolate

Juyoun Shin, Kwan Soo Ko

Department of Microbiology

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Plasmid pKP12226 was extracted and analyzed from a CTX-M-15-producing Klebsiella pneumoniae sequence type 11 (ST11) isolate collected in South Korea. The plasmid represents chimeric characteristics consisting of a pIP1206-like backbone and lysogenized phage P1-like sequences. It bears a resistance region that includes resistance genes to several antibiotics and is different from previously characterized plasmids from South Korea bearing bla_CTX-M-15. It may have resulted from recombination between an Escherichia coli plasmid backbone, a bla_CTX-M-15-bearing resistance region, and lysogenized phage P1-like sequences.

Original language	English
Pages (from-to)	6608-6610
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	59
Issue number	10
DOIs	https://doi.org/10.1128/AAC.00265-15
State	Published - 1 Oct 2015

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title = "A Plasmid bearing the blaCTX-M-15 gene and phage P1-like sequences from a sequence type 11 Klebsiella pneumoniae isolate",

abstract = "Plasmid pKP12226 was extracted and analyzed from a CTX-M-15-producing Klebsiella pneumoniae sequence type 11 (ST11) isolate collected in South Korea. The plasmid represents chimeric characteristics consisting of a pIP1206-like backbone and lysogenized phage P1-like sequences. It bears a resistance region that includes resistance genes to several antibiotics and is different from previously characterized plasmids from South Korea bearing blaCTX-M-15. It may have resulted from recombination between an Escherichia coli plasmid backbone, a blaCTX-M-15-bearing resistance region, and lysogenized phage P1-like sequences.",

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AU - Ko, Kwan Soo

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N2 - Plasmid pKP12226 was extracted and analyzed from a CTX-M-15-producing Klebsiella pneumoniae sequence type 11 (ST11) isolate collected in South Korea. The plasmid represents chimeric characteristics consisting of a pIP1206-like backbone and lysogenized phage P1-like sequences. It bears a resistance region that includes resistance genes to several antibiotics and is different from previously characterized plasmids from South Korea bearing blaCTX-M-15. It may have resulted from recombination between an Escherichia coli plasmid backbone, a blaCTX-M-15-bearing resistance region, and lysogenized phage P1-like sequences.

AB - Plasmid pKP12226 was extracted and analyzed from a CTX-M-15-producing Klebsiella pneumoniae sequence type 11 (ST11) isolate collected in South Korea. The plasmid represents chimeric characteristics consisting of a pIP1206-like backbone and lysogenized phage P1-like sequences. It bears a resistance region that includes resistance genes to several antibiotics and is different from previously characterized plasmids from South Korea bearing blaCTX-M-15. It may have resulted from recombination between an Escherichia coli plasmid backbone, a blaCTX-M-15-bearing resistance region, and lysogenized phage P1-like sequences.

UR - https://www.scopus.com/pages/publications/84942896882

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JF - Antimicrobial Agents and Chemotherapy

IS - 10

ER -

A Plasmid bearing the bla_CTX-M-15 gene and phage P1-like sequences from a sequence type 11 Klebsiella pneumoniae isolate

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