A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

Sung Wan Jang; Won Se Suh; Chung Sub Kim; Ki Hyun Kim; Kang Ro Lee

doi:10.1007/s12272-015-0610-y

A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

Sung Wan Jang, Won Se Suh, Chung Sub Kim, Ki Hyun Kim, Kang Ro Lee

Department of Pharmacy

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-β-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.

Original language	English
Pages (from-to)	1943-1951
Number of pages	9
Journal	Archives of Pharmacal Research
Volume	38
Issue number	11
DOIs	https://doi.org/10.1007/s12272-015-0610-y
State	Published - 1 Nov 2015

Keywords

Cytotoxicity
Phenolic glycoside
Spiraea prunifolia var. simpliciflora

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10.1007/s12272-015-0610-y

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title = "A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs",

abstract = "The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-β-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.",

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doi = "10.1007/s12272-015-0610-y",

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T1 - A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

AU - Jang, Sung Wan

AU - Suh, Won Se

AU - Kim, Chung Sub

AU - Kim, Ki Hyun

AU - Lee, Kang Ro

PY - 2015/11/1

Y1 - 2015/11/1

N2 - The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-β-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.

AB - The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-β-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.

KW - Cytotoxicity

KW - Phenolic glycoside

KW - Spiraea prunifolia var. simpliciflora

UR - https://www.scopus.com/pages/publications/84947125862

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DO - 10.1007/s12272-015-0610-y

M3 - Article

C2 - 25925344

AN - SCOPUS:84947125862

SN - 0253-6269

VL - 38

SP - 1943

EP - 1951

JO - Archives of Pharmacal Research

JF - Archives of Pharmacal Research

IS - 11

ER -

A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

Abstract

Keywords

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