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A natural and biodegradable scaffold of electrospun eggshell membrane

  • W. D. Kim
  • , T. Min
  • , S. A. Park
  • , J. H. Park
  • , G. H. Kim
  • Korea Institute of Machinery and Materials

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A successful tissue-engineering scaffold must have a highly porous structure and good mechanical stability. High porosity and optimally designed pore size provide structural space for cell accommodation and migration and enable the exchange of nutrients between the scaffold and cell culturing environment. The pore structures should be interconnected with each other for cell growth and proliferation. Soluble eggshell membrane protein (SEP) was prepared from eggshell membrane (ESM) and mixed with poly(-caprolactone) (PCL) solutions. SEP/PCL micro-size-fibre web was fabricated using electrospinning process with the help of a dual nozzle and auxiliary cylindrical electrode. The web was characterized with water contact angle (WCA) and cellular behaviour. The SEP/PCL web, which showed feasibility to fabricate scaffold having adequate hydrophilicity and suitable pore distribution, was a good example mimicking the natural biomaterial.

Original languageEnglish
Title of host publicationComputational Methods and Experiments in Materials Characterisation III
Pages349-358
Number of pages10
DOIs
StatePublished - 2007
Externally publishedYes
Event3rd International Conference on Computational Methods and Experiments in Material Characterisation 2007 - Bologna, Italy
Duration: 13 Jun 200715 Jun 2007

Publication series

NameWIT Transactions on Engineering Sciences
Volume57
ISSN (Print)1743-3533

Conference

Conference3rd International Conference on Computational Methods and Experiments in Material Characterisation 2007
Country/TerritoryItaly
CityBologna
Period13/06/0715/06/07

Keywords

  • Biomimic
  • Nanofibre
  • Poly(-caprolactone)
  • Soluble eggshell protein

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