A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6

Tae Il Kim; Hyo Jin Kang; Garam Han; Sang J. Chung; Youngmi Kim

doi:10.1039/b911145j

A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6

Tae Il Kim
, Hyo Jin Kang
, Garam Han
, Sang J. Chung
, Youngmi Kim

Dankook University
Korea Research Institute of Bioscience and Biotechnology

Research output: Contribution to journal › Article › peer-review

152 Scopus citations

Abstract

A highly selective fluorescent probe for a protein tyrosine phosphatase (PTP) was designed by a simple phosphorylation of the 2-(2′-hydroxyphenyl) benzothiazole (HBT) chromophore: upon selective enzymatic hydrolysis, an excited-state intramolecular proton transfer (ESIPT) occurs, resulting in a large Stokes shift.

Original language	English
Pages (from-to)	5895-5897
Number of pages	3
Journal	Chemical Communications
Issue number	39
DOIs	https://doi.org/10.1039/b911145j
State	Published - 2009
Externally published	Yes

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10.1039/b911145j

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title = "A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6",

abstract = "A highly selective fluorescent probe for a protein tyrosine phosphatase (PTP) was designed by a simple phosphorylation of the 2-(2′-hydroxyphenyl) benzothiazole (HBT) chromophore: upon selective enzymatic hydrolysis, an excited-state intramolecular proton transfer (ESIPT) occurs, resulting in a large Stokes shift.",

author = "Kim, \{Tae Il\} and Kang, \{Hyo Jin\} and Garam Han and Chung, \{Sang J.\} and Youngmi Kim",

year = "2009",

doi = "10.1039/b911145j",

language = "English",

pages = "5895--5897",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6

AU - Kim, Tae Il

AU - Kang, Hyo Jin

AU - Han, Garam

AU - Chung, Sang J.

AU - Kim, Youngmi

PY - 2009

Y1 - 2009

N2 - A highly selective fluorescent probe for a protein tyrosine phosphatase (PTP) was designed by a simple phosphorylation of the 2-(2′-hydroxyphenyl) benzothiazole (HBT) chromophore: upon selective enzymatic hydrolysis, an excited-state intramolecular proton transfer (ESIPT) occurs, resulting in a large Stokes shift.

AB - A highly selective fluorescent probe for a protein tyrosine phosphatase (PTP) was designed by a simple phosphorylation of the 2-(2′-hydroxyphenyl) benzothiazole (HBT) chromophore: upon selective enzymatic hydrolysis, an excited-state intramolecular proton transfer (ESIPT) occurs, resulting in a large Stokes shift.

UR - https://www.scopus.com/pages/publications/70349656536

U2 - 10.1039/b911145j

DO - 10.1039/b911145j

M3 - Article

C2 - 19787133

AN - SCOPUS:70349656536

SN - 1359-7345

SP - 5895

EP - 5897

JO - Chemical Communications

JF - Chemical Communications

IS - 39

ER -

A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6

Abstract

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