A compact SPECT/CT for small animal imaging

  • Key Jo Hong
  • , Yong Choi
  • , Sang Chul Lee
  • , Soo Yeol Lee
  • , Tae Yong Song
  • , Byung Jun Min
  • , Jin Ho Jung
  • , J. Y. Choi
  • , Yearn Seong Choe
  • , Kyung Han Lee
  • , Byung Tae Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A dual-modality compact SPECT/CT system for small animal imaging has been developed. The SPECT system consisted of a pinhole collimator and plate type Nal(Tl) scintillation crystal coupled to a PSPMT. The X-ray system consisted of a microfocus X-ray tube and a CMOS flat-panel detector. The SPECT system was mounted perpendicular to the X-ray system. Individual projections of SPECT and CT were acquired by rotating the animal about a vertical axis in front of the detectors. The SPECT and CT image were reconstructed using OSEM and Feldkamp's cone-beam algorithms, respectively. Mouse and rat SPECT demonstrated detailed activity distributions at the expected structures. A CT image obtained with 40 kVp and 0.5 mA presented high-resolution anatomic details. Fused SPECT/CT images demonstrated good agreement between the CT images and the corresponding uptake of the radiotracer. The SPECT/CT system developed in this study provides high-quality dual-modality images and could be useful to obtain functional images with high-resolution morphology information.

Original languageEnglish
Title of host publication2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Pages2191-2194
Number of pages4
DOIs
StatePublished - 2005
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: 23 Oct 200529 Oct 2005

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume4
ISSN (Print)1095-7863

Conference

ConferenceNuclear Science Symposium Conference Record, 2005 IEEE
Country/TerritoryPuerto Rico
Period23/10/0529/10/05

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