A case of valproic acid induced DRESS syndrome

Yoon Hwan Kim; Chong Won Choi; Ga Young Lee; Won Serk Kim

A case of valproic acid induced DRESS syndrome

Yoon Hwan Kim, Chong Won Choi, Ga Young Lee, Won Serk Kim

Kangbuk Samsung Hospital

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

DRESS syndrome is an uncommon but potentially life-threatening subset of severe drug eruption characterized by fever, rash, leukocytosis with eosinophilia or atypical lymphocytosis, lymphadenopathy, and liver or renal dysfunction. The aromatic anticonvulsants (phenytoin, phenobarbital, carbamazepine) and sulfonamides are the most common cause of DRESS syndrome. Valproic acid, which is a widely used non-aromatic anticonvulsant, rarely causes DRESS syndrome. We report a case of DRESS syndrome in 47-year-old man caused by the use of valproic acid.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	Korean Journal of Dermatology
Volume	50
Issue number	1
State	Published - Jan 2012
Externally published	Yes

Keywords

DRESS syndrome
Valproic acid

Cite this

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title = "A case of valproic acid induced DRESS syndrome",

abstract = "DRESS syndrome is an uncommon but potentially life-threatening subset of severe drug eruption characterized by fever, rash, leukocytosis with eosinophilia or atypical lymphocytosis, lymphadenopathy, and liver or renal dysfunction. The aromatic anticonvulsants (phenytoin, phenobarbital, carbamazepine) and sulfonamides are the most common cause of DRESS syndrome. Valproic acid, which is a widely used non-aromatic anticonvulsant, rarely causes DRESS syndrome. We report a case of DRESS syndrome in 47-year-old man caused by the use of valproic acid.",

keywords = "DRESS syndrome, Valproic acid",

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AU - Kim, Yoon Hwan

AU - Choi, Chong Won

AU - Lee, Ga Young

AU - Kim, Won Serk

PY - 2012/1

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N2 - DRESS syndrome is an uncommon but potentially life-threatening subset of severe drug eruption characterized by fever, rash, leukocytosis with eosinophilia or atypical lymphocytosis, lymphadenopathy, and liver or renal dysfunction. The aromatic anticonvulsants (phenytoin, phenobarbital, carbamazepine) and sulfonamides are the most common cause of DRESS syndrome. Valproic acid, which is a widely used non-aromatic anticonvulsant, rarely causes DRESS syndrome. We report a case of DRESS syndrome in 47-year-old man caused by the use of valproic acid.

AB - DRESS syndrome is an uncommon but potentially life-threatening subset of severe drug eruption characterized by fever, rash, leukocytosis with eosinophilia or atypical lymphocytosis, lymphadenopathy, and liver or renal dysfunction. The aromatic anticonvulsants (phenytoin, phenobarbital, carbamazepine) and sulfonamides are the most common cause of DRESS syndrome. Valproic acid, which is a widely used non-aromatic anticonvulsant, rarely causes DRESS syndrome. We report a case of DRESS syndrome in 47-year-old man caused by the use of valproic acid.

KW - DRESS syndrome

KW - Valproic acid

UR - https://www.scopus.com/pages/publications/84863133687

M3 - Article

AN - SCOPUS:84863133687

SN - 0494-4739

VL - 50

SP - 85

EP - 88

JO - Korean Journal of Dermatology

JF - Korean Journal of Dermatology

IS - 1

ER -

A case of valproic acid induced DRESS syndrome

Abstract

Keywords

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