Abstract
Generalized pustular psoriasis is a lethal variant of psoriasis characterized by the appearance of sterile pustules on psoriatic skin. Etretinate and acitretin are effective in pustular forms of psoriasis, including generalized pustular psoriasis. A major concern with the use of systemic retinoid is their high teratogenic potential. Since etretinate and acitretin are remetabolized into long-lived compounds, isotretinoin may be used to treat women of childbearing years with generalized pustular psoriasis. We report a case of generalized pustular psoriasis in a 28-year-old woman whose condition was improved with isotretinoin. Clinical improvement was noted with the administration of isotretinoin at the dose of 30mg/day.
| Original language | English |
|---|---|
| Pages (from-to) | 1667-1669 |
| Number of pages | 3 |
| Journal | Korean Journal of Dermatology |
| Volume | 41 |
| Issue number | 12 |
| State | Published - Dec 2003 |
Keywords
- Generalized pustular psoriasis
- Isotretinoin