3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration

Jiun Lee; Soo Jung Chae; Wonjin Kim; Jaeyoon Lee; Miji Yeo; Gi Hoon Yang; Haeri Kim; Youngeun Choe; Youngwon Koo; Geunhyung Kim

3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration

Jiun Lee
, Soo Jung Chae
, Wonjin Kim
, Jaeyoon Lee
, Miji Yeo
, Gi Hoon Yang
, Haeri Kim
, Youngeun Choe
, Youngwon Koo
, Geunhyung Kim

Department of Precision Medicine

Sungkyunkwan University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Statement of Purpose: Human bone tissue is mainly composed of hydroxyapatite and collagen type I. [1] Based on this information, diverse researches have been done to fabricate this component mimic scaffolds for bone tissue regeneration. Moreover, to enhance the bone regeneration, growth factors release ability also needed. [2] In this study, we fabricate 3D calcium deficient hydroxyapatite (CDHA)/collagen/platelet rich plasma (PRP) composite scaffolds with sustained release of growth factors using 3D printing system. The growth factors, such as transforming growth factor-β1 (TGF-β1) and platelet derived growth factors (PDGF), were released from the scaffolds until 35 days.

Original language	English
Title of host publication	Society for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publication	The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
Publisher	Society for Biomaterials
Pages	552
Number of pages	1
ISBN (Electronic)	9781510883901
State	Published - 2019
Event	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States Duration: 3 Apr 2019 → 6 Apr 2019

Publication series

Name	Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume	40
ISSN (Print)	1526-7547

Conference

Conference	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Country/Territory	United States
City	Seattle
Period	3/04/19 → 6/04/19

Cite this

Lee, J., Chae, S. J., Kim, W., Lee, J., Yeo, M., Yang, G. H., Kim, H., Choe, Y., Koo, Y., & Kim, G. (2019). 3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (pp. 552). (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.

Lee, Jiun ; Chae, Soo Jung ; Kim, Wonjin et al. / 3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration. Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. pp. 552 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).

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title = "3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration",

abstract = "Statement of Purpose: Human bone tissue is mainly composed of hydroxyapatite and collagen type I. [1] Based on this information, diverse researches have been done to fabricate this component mimic scaffolds for bone tissue regeneration. Moreover, to enhance the bone regeneration, growth factors release ability also needed. [2] In this study, we fabricate 3D calcium deficient hydroxyapatite (CDHA)/collagen/platelet rich plasma (PRP) composite scaffolds with sustained release of growth factors using 3D printing system. The growth factors, such as transforming growth factor-β1 (TGF-β1) and platelet derived growth factors (PDGF), were released from the scaffolds until 35 days.",

author = "Jiun Lee and Chae, \{Soo Jung\} and Wonjin Kim and Jaeyoon Lee and Miji Yeo and Yang, \{Gi Hoon\} and Haeri Kim and Youngeun Choe and Youngwon Koo and Geunhyung Kim",

note = "Publisher Copyright: {\textcopyright} 2019 Omnipress - All rights reserved.; 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",

year = "2019",

language = "English",

series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",

publisher = "Society for Biomaterials",

pages = "552",

booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",

}

Lee, J, Chae, SJ, Kim, W, Lee, J, Yeo, M, Yang, GH, Kim, H, Choe, Y, Koo, Y & Kim, G 2019, 3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration. in Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, Society for Biomaterials, pp. 552, 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence, Seattle, United States, 3/04/19.

3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration. / Lee, Jiun; Chae, Soo Jung; Kim, Wonjin et al.
Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. p. 552 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - 3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration

AU - Lee, Jiun

AU - Chae, Soo Jung

AU - Kim, Wonjin

AU - Lee, Jaeyoon

AU - Yeo, Miji

AU - Yang, Gi Hoon

AU - Kim, Haeri

AU - Choe, Youngeun

AU - Koo, Youngwon

AU - Kim, Geunhyung

PY - 2019

Y1 - 2019

N2 - Statement of Purpose: Human bone tissue is mainly composed of hydroxyapatite and collagen type I. [1] Based on this information, diverse researches have been done to fabricate this component mimic scaffolds for bone tissue regeneration. Moreover, to enhance the bone regeneration, growth factors release ability also needed. [2] In this study, we fabricate 3D calcium deficient hydroxyapatite (CDHA)/collagen/platelet rich plasma (PRP) composite scaffolds with sustained release of growth factors using 3D printing system. The growth factors, such as transforming growth factor-β1 (TGF-β1) and platelet derived growth factors (PDGF), were released from the scaffolds until 35 days.

AB - Statement of Purpose: Human bone tissue is mainly composed of hydroxyapatite and collagen type I. [1] Based on this information, diverse researches have been done to fabricate this component mimic scaffolds for bone tissue regeneration. Moreover, to enhance the bone regeneration, growth factors release ability also needed. [2] In this study, we fabricate 3D calcium deficient hydroxyapatite (CDHA)/collagen/platelet rich plasma (PRP) composite scaffolds with sustained release of growth factors using 3D printing system. The growth factors, such as transforming growth factor-β1 (TGF-β1) and platelet derived growth factors (PDGF), were released from the scaffolds until 35 days.

UR - https://www.scopus.com/pages/publications/85065388353

M3 - Conference contribution

AN - SCOPUS:85065388353

T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium

SP - 552

BT - Society for Biomaterials Annual Meeting and Exposition 2019

PB - Society for Biomaterials

T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence

Y2 - 3 April 2019 through 6 April 2019

ER -

Lee J, Chae SJ, Kim W, Lee J, Yeo M, Yang GH et al. 3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials. 2019. p. 552. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).

3d printed calcium deficient hydroxyapatite/collagen/platelet rich plasma composite scaffolds functionalized with sustained release of growth factor for bone tissue regeneration

Abstract

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