3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a] quinoline-6-carboxylic acid: Synthesis and In vitro cytotoxic activity

Dong H. Kim; Sang J. Chung; Seung Woo Yeon

doi:10.1016/0960-894X(95)00338-T

3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a] quinoline-6-carboxylic acid: Synthesis and In vitro cytotoxic activity

Dong H. Kim
, Sang J. Chung
, Seung Woo Yeon

Pohang University of Science and Technology
Ildong Pharmaceutical Co., Ltd.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The title compound which shows a potent in vitro cytotoxic activity has been synthesized employing the tandem double ring closure reaction of N-acyl-N-(2′-hydroxyphenyl) anthranilic acid with acetic anhydride as a key step.

Original language	English
Pages (from-to)	1953-1956
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	5
Issue number	17
DOIs	https://doi.org/10.1016/0960-894X(95)00338-T
State	Published - 7 Sep 1995
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/0960-894X(95)00338-T

Cite this

@article{718f70386550433188f8a568698ef37c,

title = "3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a] quinoline-6-carboxylic acid: Synthesis and In vitro cytotoxic activity",

abstract = "The title compound which shows a potent in vitro cytotoxic activity has been synthesized employing the tandem double ring closure reaction of N-acyl-N-(2′-hydroxyphenyl) anthranilic acid with acetic anhydride as a key step.",

author = "Kim, \{Dong H.\} and Chung, \{Sang J.\} and Yeon, \{Seung Woo\}",

year = "1995",

month = sep,

day = "7",

doi = "10.1016/0960-894X(95)00338-T",

language = "English",

volume = "5",

pages = "1953--1956",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd",

number = "17",

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TY - JOUR

T1 - 3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a] quinoline-6-carboxylic acid

T2 - Synthesis and In vitro cytotoxic activity

AU - Kim, Dong H.

AU - Chung, Sang J.

AU - Yeon, Seung Woo

PY - 1995/9/7

Y1 - 1995/9/7

N2 - The title compound which shows a potent in vitro cytotoxic activity has been synthesized employing the tandem double ring closure reaction of N-acyl-N-(2′-hydroxyphenyl) anthranilic acid with acetic anhydride as a key step.

AB - The title compound which shows a potent in vitro cytotoxic activity has been synthesized employing the tandem double ring closure reaction of N-acyl-N-(2′-hydroxyphenyl) anthranilic acid with acetic anhydride as a key step.

UR - https://www.scopus.com/pages/publications/0029084677

U2 - 10.1016/0960-894X(95)00338-T

DO - 10.1016/0960-894X(95)00338-T

M3 - Article

AN - SCOPUS:0029084677

SN - 0960-894X

VL - 5

SP - 1953

EP - 1956

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 17

ER -

3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a] quinoline-6-carboxylic acid: Synthesis and In vitro cytotoxic activity

Abstract

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